Package leaflet · information for the user
Yohimbine Hydrochloride 10 mg
Yohimbine Hydrochloride
Read all of this leaflet carefully before you start using this medicine
- Keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
- If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.
1.What Yohimbine Hydrochloride is and what it is used for
Yohimbine is a tablet made from a substance found in the bark of a tree. It blocks a particular nerve signal in the body, which widens some blood vessels, increases blood flow and raises the activity of the nervous system. Because of this it also raises blood pressure and heart rate. Your doctor has prescribed it for you after weighing up whether it is suitable. It is prescription-only and must not be taken by anyone else.
2.What you need to know before you use Yohimbine Hydrochloride
This medicine acts strongly on blood pressure and on mood, so your doctor needs a full picture of your health and your other medicines first.
Do not use it if
- Do not use yohimbine if you are allergic to yohimbine or to any of the other ingredients listed in section 6.
- Do not use yohimbine if you have high blood pressure, or blood pressure that is not well controlled.
- Do not use yohimbine if you have heart disease, angina, an irregular heartbeat, or have had a heart attack or a stroke.
- Do not use yohimbine if you have kidney disease or liver disease.
- Do not use yohimbine if you have anxiety, panic attacks, bipolar disorder, schizophrenia or another mental health condition, as it can make these much worse.
- Do not use yohimbine if you are taking a medicine called a monoamine oxidase inhibitor (a type of antidepressant), or have taken one in the last two weeks.
- Do not use yohimbine if you are pregnant or breastfeeding.
- Do not use yohimbine if you have a stomach ulcer or a duodenal ulcer.
Warnings and precautions
- Talk to your doctor before using yohimbine if you have ever had raised blood pressure or have been told to watch it. Your blood pressure and pulse should be checked before you start and while you are taking it.
- Talk to your doctor before using yohimbine if you have ever felt anxious, panicky or very low, because this medicine can bring those feelings on or make them stronger.
- Talk to your doctor before using yohimbine if you have an enlarged prostate or difficulty passing urine.
- Talk to your doctor before using yohimbine if you have diabetes, as this medicine may change your blood sugar.
- Talk to your doctor if you feel your heart racing, get a bad headache, feel very anxious, or feel dizzy when you stand up. Do not simply continue and hope it passes.
- Avoid drinks and tablets containing caffeine while you take this medicine, and avoid alcohol, as both can make the shaking, fast heartbeat and anxiety worse.
- This medicine is not a treatment for weight loss or for sports performance, and must never be used for that. Doing so can cause dangerous rises in blood pressure.
Other medicines and Yohimbine Hydrochloride
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including ones bought without a prescription, herbal products and supplements. It is especially important to mention any medicine for blood pressure, including clonidine, as yohimbine works against them and can make your blood pressure rise; antidepressants of every kind, particularly monoamine oxidase inhibitors, which must not be combined with yohimbine; medicines for anxiety or for mental health; stimulants, including decongestants for a blocked nose and diet products; medicines for an irregular heartbeat; and diabetes medicines. Herbal stimulants and high-caffeine products should also be mentioned, because they add to the effect on your heart and blood pressure.
Pregnancy, breastfeeding and fertility
Do not take yohimbine if you are pregnant, think you may be pregnant, or are planning to become pregnant. It has not been shown to be safe in pregnancy and can affect blood pressure and the nervous system. Do not take it while breastfeeding, as it is not known whether it passes into breast milk. If you could become pregnant, talk to your doctor about reliable contraception, and tell your doctor at once if you become pregnant while taking this medicine. Ask your doctor or pharmacist for advice before taking any medicine.
Driving and using machines
Yohimbine can make you feel dizzy, shaky, anxious or light-headed, and can make it hard to sleep, so you may be tired the next day. Do not drive, cycle or use tools or machines if you are affected. Take extra care when you stand up from sitting or lying, as you may feel faint.
3.How to use Yohimbine Hydrochloride
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. It is a tablet that you swallow whole with a drink of water. Because it can keep you awake, your doctor will usually tell you to avoid taking it late in the day. Your doctor decides the amount and how long you take it, and will normally start low and review how you respond, so never take more than you have been told to and never take it more often. Do not take it with caffeine or alcohol. If you forget a tablet, skip it and carry on with the next one at the usual time; do not take a double amount to make up for a forgotten one. If you take more tablets than you were told to, contact your doctor or go to the nearest hospital straight away, and take the pack with you, because too much can cause a dangerous rise in blood pressure.
4.Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Stop and get medical help straight away
- A very bad headache with a pounding heart, chest pain or blurred sight, which can mean your blood pressure has risen dangerously. Get medical help now.
- Chest pain, or a heartbeat that is fast, irregular or pounding and does not settle. Get medical help now.
- A panic attack, severe agitation, confusion, hallucinations, or thoughts of harming yourself. Get medical help now.
- Fainting, collapsing, or a fit (seizure). Call the emergency services.
- A severe allergic reaction: swelling of the face, lips, tongue or throat, difficulty breathing or swallowing, or a sudden severe rash. Get emergency help at once.
- An erection that is painful or lasts more than four hours. Go to the nearest hospital at once, as this needs urgent treatment.
Other possible side effects
- Feeling anxious, restless, nervous or on edge
- A fast or pounding heartbeat
- A rise in blood pressure
- Difficulty sleeping
- Headache
- Shaking or trembling
- Sweating and flushing
- Feeling dizzy, especially when standing up
- Feeling sick, being sick, or stomach discomfort
- Needing to pass urine more often, or difficulty passing urine
- Tingling or a prickling feeling in the skin
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist — including any not listed in this leaflet. You can also report them directly to us at pv@ergopharm.net or through our reporting form, and to your national reporting system. By reporting side effects you help provide more information on the safety of this medicine.
5.How to store Yohimbine Hydrochloride
Keep this medicine out of the sight and reach of children. Store below 30 degrees Celsius in the original pack, protected from light and moisture. Do not use this medicine after the expiry date printed on the carton and the blister foil; the expiry date refers to the last day of that month. Do not use the tablets if the blister is torn or the tablets look damaged or discoloured. Do not throw medicines away in your household waste or down the toilet. Take any medicine you no longer need back to your pharmacy for safe disposal. This helps protect the environment.
6.Contents of the pack and other information
Each tablet contains yohimbine hydrochloride as the active substance. The other ingredients are the fillers, binder and lubricant that form the tablet; the full list is printed on the carton. The tablets are plain, uncoated and round, and are supplied in blister strips inside a cardboard carton, in packs of 10 to 100 tablets. Not all pack sizes may be available in your country. Each carton carries a printed square barcode (a GS1 DataMatrix) and a verification code that you can enter at ergopharm.net to confirm that the pack is genuine. Manufactured under GMP conditions by Ergopharm, Vadodara, Gujarat, India.