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2024 · 09PIC/SRegulatory Notices

Procedures reviewed against PIC/S PE 009-17

Ergopharm has completed a review of its GMP procedures against PIC/S PE 009-17, the current revision of the PIC/S Guide to Good Manufacturing Practice.

The PIC/S guide tracks EU GMP closely, and the review was principally a confirmation exercise: comparing each chapter and annex against the corresponding site procedure and recording either conformity or an action. The value of doing it formally is that it produces a documented map rather than a general confidence.

A documented map beats a general feeling that we are probably compliant.

The review paid particular attention to the annexes that bear on the site's operations — sterile manufacture, computerised systems, qualification and validation, and certification by the authorised person — and to the data-integrity guidance in PIC/S PI 041-1.

Gaps identified were raised through change control with owners and dates, and closed under the normal quality system rather than as a special project.

Key facts

Reference
PIC/S PE 009-17
Method
Chapter-by-chapter comparison against site procedures
Focus
Sterile, computerised systems, qualification, certification
Data integrity
PIC/S PI 041-1

This notice describes Ergopharm’s own packaging and processes and how they follow published standards; it does not assert a specific national marketing approval.